What goes into a doctor’s selection of which medication to try first if you have ADHD?

Harold Robert Meyer and The ADD Resource Center                             01/28/2025 

A doctor typically considers several key factors when selecting an initial ADHD medication:

  1. Age and Medical History: First, they’ll consider your age (whether you’re a child, adolescent, or adult) and review your medical history, including:
  • Heart conditions
  • Blood pressure
  • History of anxiety or mood disorders
  • History of drug or alcohol abuse
  • Family history of cardiovascular issues
  • Co-occurring conditions
  • Other medications you’re taking
  1. Type and Severity of Symptoms: They’ll evaluate which ADHD symptoms are most problematic for you:
  • Difficulty focusing
  • Hyperactivity
  • Impulsivity
  • Impact on daily functioning
  1. Medication Classes: They’ll typically choose between two main categories:
  • Stimulants (like methylphenidate or amphetamines) are usually tried first as they’re effective for about 70-80% of people
  • Non-stimulants (like atomoxetine or guanfacine) might be chosen first if there are concerns about stimulant use
  1. Practical Considerations:

Whether you can swallow pills or need liquid/chewable forms

Insurance coverage and medication costs

Whether you need the medication to work primarily during school/work hours or throughout the day

Your ability to remember to take medications multiple times per day

© 2025 The ADD Resource Center. All rights reserved. 01/28/2025

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