Clinical Trials: Information for Participants


Clinical research trials are at the heart of all medical advances. Researchers enroll women, men, and children in clinical trials to test new ways to prevent, detect, or treat disease. Studies often enroll people with a specific disorder but some also accept people without health problems to provide baseline information on overall health.

To learn the basics about clinical trials, check out NIMH’s Clinical Research Trials and You: Questions and Answers brochure or visit the NIH Clinical Trials and You website.

Read transcript.

Why Participate in Clinical Research?

People participate in clinical trials for various reasons. Healthy volunteers say they participate to help others and contribute to moving science forward. Participants with an illness or disease also participate to help others, possibly receive the newest treatment, and receive additional care and attention from the clinical trial staff.

Clinical trials offer hope for many people and an opportunity to help researchers find better treatments for others in the future.

Join a Study at NIMH

NIMH, part of the National Institutes of Health (NIH), supports research studies through its Intramural Division on the NIH campus in Bethesda, Maryland. These studies enroll eligible participants from across the U.S. You can also learn more about studies conducted at the NIH using the following links:

Please subscribe and select Intramural Updates to receive periodic updates on mental health research, including news, resources, educational events, and clinical research studies conducted at the NIH Clinical Center.

Find a Study Near You

NIMH funds many research studies through grants to researchers around the country. Find ongoing studies that are currently recruiting participants:

Other Ways To Find a Clinical Trial Near You:

  • Talk to your health care provider about local studies that may be right for you.
  • Search, the National Institutes of Health (NIH)/National Library of Medicine’s registry of federally and privately funded clinical trial conditions at NIH and across the country for a variety of diseases and conditions. You can also learn more about how to participate, refer a patient, or learn about results of studies. Please contact each research study team to learn more specifics. If you qualify for a study, then a study-related evaluation, treatment and, in some cases transportation to NIH is provided without cost to you or your health plan.
  • Join a National Registry of Research Volunteers, such as ResearchMatch. This NIH-funded initiative connects 1) people who are trying to find research studies and 2) researchers seeking people to participate in their studies. It is a free, secure registry that makes it easier for the public to volunteer and become involved in clinical research studies that contribute to improved health in the future.

Learn More

Contact Information

  • For more information about clinical trials conducted at NIMH, visit:
  • Join A Study.
  • For questions about participating in research studies that are being conducted at the National Institutes of Health and where to find them, contact (link sends e-mail).
  • For a listing of clinical trials being conducted around the country by NIH and others, be sure to check the website.

Free NIMH Brochures and Fact Sheets

  • This brochure provides information on clinical trials, including who participates in them and why, as well as guidelines. It is also available in Spanish.

Federal Resources

Information for Researchers


  • Watch: Addictive Behaviors: Carl Lejuez, Professor of Clinical Psychology at the University of Maryland, College Park, and Director of the Center for Addictions, Personality & Emotional Research, discusses translational research studying the basic internal processes that lead people to addictive behaviors.
  • Watch: National Database for Autism Research (NDAR) The National Database for Autism Research provides a way for scientists share data on human autism studies. Families with autism can accelerate discoveries by participating in research and consenting to have their data shared.
  • Watch Videos sobre la investigación clínica, a series of Spanish-language NIH videos about participating in research.
  • Watch the Participating in Research Video Series developed by the HHS Office for Human Research Protection about participating in research.

Recent Posts

When And How to Write a Thank You Letter or Email

Remember to always send a thank-you letter or email and know the appropriate timing and…

1 day ago

From Chaos to Clarity: Cultivating Intentional Thinking with ADHD

This essay explores the journey from this state of haphazard thinking to a more intentional,…

2 days ago

How to Prepare for a Phone Call When You Have ADHD

For individuals with ADHD, phone calls can be challenging due to difficulties with organization, focus,…

3 days ago

Home-schooling Your Child with ADHD: A Personalized Approach.

In this article, we explore some strategies and tips to help you successfully home-school your…

5 days ago

Is your young child’s behavior simply age-appropriate, or could it be ADHD?

It's important to distinguish between typical age-appropriate behavior and potential signs of ADHD

1 week ago

Understanding ADHD and Fear of Intimacy: Why We Push Loved Ones Away

Understanding the interplay between ADHD and fear of intimacy is essential, as this relationship dynamic…

2 weeks ago