Is There a Peer Reviewed Relationship Between ADHD and Premenstrual Syndrome, or PMS?

There is emerging evidence suggesting a potential relationship between ADHD (Attention-Deficit/Hyperactivity Disorder) and premenstrual syndrome (PMS) or premenstrual dysphoric disorder (PMDD). Some studies have found a high prevalence of PMDD and PMS symptoms in women with ADHD. This could be due to hormonal changes across the menstrual cycle that may affect neurotransmitters like dopamine, which is implicated in ADHD. Therefore, ADHD symptoms may change across the menstrual cycle in response to these endogenous steroid changes. However, the relationship between ADHD and menstrual cycle characteristics, including PMS, is complex and not fully understood.

More research is needed to understand better this relationship and its implications for the management of women with ADHD.

As always, it’s important to consider the individual patient’s symptoms and experiences and to provide a comprehensive approach to care that addresses all aspects of their health and well-being. Clinicians and others should be aware of the potential for increased ADHD symptoms or mood disorder symptoms in women with ADHD during different phases of the menstrual cycle and adjust treatment plans accordingly.


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