Harold Robert Meyer and The ADD Resource Center                              05/08/2025 

This is not medical advice. Do not make any changes without first consulting your medical practitioner.

ADHD medications, particularly stimulants like methylphenidate and amphetamines, can sometimes become less effective over time due to the development of tolerance. Tolerance occurs when the body becomes accustomed to a drug, leading to a reduction in its effectiveness. This can happen with some patients over days to weeks, while others may not experience it at all.

If a patient develops tolerance to ADHD medication, several strategies can be considered:

1.  Medication Review: Re-evaluate the current medication regimen with a healthcare provider to determine if adjustments are needed.

2. Dose Adjustment: Sometimes, adjusting the dose can help regain effectiveness, but this should only be done under medical supervision.

3. Medication Holidays: In some cases, taking breaks from medication (under medical guidance) can help reduce tolerance.

4. Switching Medications: Trying a different medication or formulation may be beneficial if tolerance develops.

5. Combination Therapy: Combining medication with behavioral therapy or other non-pharmacological interventions can enhance overall treatment effectiveness.

6. Lifestyle Modifications: Incorporating regular exercise, a balanced diet, and good sleep hygiene can support medication efficacy and overall symptom management.

It’s essential for patients to work closely with their healthcare provider to tailor their treatment plan to their individual needs and circumstances.

  __________________________________________________ ___________________

The information in this email is for educational purposes only and is not medical advice. 

Please verify its accuracy. Consult a healthcare professional before making decisions 

based on this email or any external links. Any action you take is at your own risk.

The ADD Resource Center (https://www.addrc.org/) is the best place to find comprehensive 

resources, help, information, tips, tricks, and techniques for working with ADHD. 

The ADD Resource Center and Hal Meyer empower individuals with ADHD, their loved ones, 

and the professionals who work with them. The ADD Resource Center and Hal Meyer provide

expert guidance and behavioral interventions to help adolescents, adults, and couples thrive. 

https://www.addrc.org/

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Machine translation to French

Ceci n’est pas un avis médical. N’apportez aucun changement sans consulter au préalable votre médecin.

Les médicaments pour le TDAH perdent-ils de leur efficacité lorsqu’ils sont pris sur une longue période?

Les médicaments pour le TDAH, en particulier les stimulants comme le méthylphénidate et les amphétamines, peuvent parfois devenir moins efficaces avec le temps en raison du développement d’une tolérance. La tolérance survient lorsque le corps s’habitue à un médicament, entraînant une réduction de son efficacité. Cela peut se produire chez certains patients en quelques jours ou semaines, tandis que d’autres peuvent ne pas l’expérimenter du tout.

Si un patient développe une tolérance aux médicaments pour le TDAH, plusieurs stratégies peuvent être envisagées:

1. Révision du traitement: Réévaluer le régime médicamenteux actuel avec un professionnel de santé pour déterminer si des ajustements sont nécessaires.
2. Ajustement de la dose: Parfois, l’ajustement de la dose peut aider à retrouver l’efficacité, mais cela ne doit être fait que sous surveillance médicale.
3. Pauses thérapeutiques: Dans certains cas, prendre des pauses médicamenteuses (sous guidance médicale) peut aider à réduire la tolérance.
4. Changement de médicament: Essayer un médicament différent ou une autre formulation peut être bénéfique si une tolérance se développe.
5. Thérapie combinée: Combiner la médication avec une thérapie comportementale ou d’autres interventions non pharmacologiques peut améliorer l’efficacité globale du traitement.
6. Modifications du mode de vie: Intégrer de l’exercice régulier, une alimentation équilibrée et une bonne hygiène de sommeil peut soutenir l’efficacité des médicaments et la gestion globale des symptômes.

Il est essentiel que les patients travaillent étroitement avec leur professionnel de santé pour adapter leur plan de traitement à leurs besoins et circonstances individuels.

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